Publications

Rapid Microbial Identification and Antibiotic Resistance Detection by Mass Spectrometric Analysis of Membrane Lipids. Liang T, Leung LM, Opene B, Fondrie WE, Lee YI, Chandler CE, Yoon SH, Doi Y, Ernst RK, Goodlett DR. Anal Chem. 2019 Jan 15;91(2):1286-1294. doi: 10.1021/acs.analchem.8b02611.

A Prospective Study of Acinetobacter baumannii Complex Isolates and Colistin Susceptibility Monitoring by Mass Spectrometry of Microbial Membrane Glycolipids. Leung LM, McElheny CL, Gardner FM, Chandler CE, Bowler SL, Mettus RT, Spychala CN, Fowler EL, Opene BNA, Myers RA, Goodlett DR, Doi Y, Ernst RK. J Clin Microbiol. 2019 Feb 27;57(3).. doi: 10.1128/JCM.01100-18. Print 2019 Mar. PMID: 30567747

Pathogen Identification Direct From Polymicrobial Specimens Using Membrane Glycolipids. Fondrie WE, Liang T, Oyler BL, Leung LM, Ernst RK, Strickland DK, Goodlett DR. Sci Rep. 2018 Oct 26;8(1):15857. doi: 10.1038/s41598-018-33681-8. PMID: 30367087

Structural modification of LPS in colistin-resistant, KPC-producing Klebsiella pneumoniae. Leung LM, Cooper VS, Rasko DA, Guo Q, Pacey MP, McElheny CL, Mettus RT, Yoon SH, Goodlett DR, Ernst RK, Doi Y. J Antimicrob Chemother. 2017 Nov 1;72(11):3035-3042. doi: 10.1093/jac/dkx234. PMID: 28961916

Identification of the ESKAPE pathogens by mass spectrometric analysis of microbial membrane glycolipids. Leung LM, Fondrie WE, Doi Y, Johnson JK, Strickland DK, Ernst RK, Goodlett DR. Sci Rep. 2017 Jul 25;7(1):6403. doi: 10.1038/s41598-017-04793-4. PMID: 28743946

Unique structural modifications are present in the lipopolysaccharide from colistin-resistant strains of Acinetobacter baumannii. Pelletier MR, Casella LG, Jones JW, Adams MD, Zurawski DV, Hazlett KR, Doi Y, Ernst RK. Antimicrob Agents Chemother. 2013 Oct;57(10):4831-40.

Unique lipid a modifications in Pseudomonas aeruginosa isolated from the airways of patients with cystic fibrosis. Ernst RK, Moskowitz SM, Emerson JC, Kraig GM, Adams KN, Harvey MD, Ramsey B, Speert DP, Burns JL, Miller SI. J Infect Dis. 2007 Oct 1;196(7):1088-92. DOI: 10.1086/521367

pmrA(Con) confers pmrHFIJKL-dependent EGTA and polymyxin resistance on msbB Salmonella by decorating lipid A with phosphoethanolamine. Murray SR, Ernst RK, Bermudes D, Miller SI, Low KB. J Bacteriol. 2007 Jul;189(14):5161-9. DOI: 10.1128/JB.01969-06